Title |
Author(s) |
IrusType |
Repository |
Item URL |
Total Downloads |
6-Oxopurine phosphoribosyltransferase: A target for the development of antimalarial drugs |
de Jersey, John; Holý, Antonín; Hocková, Dana; Naesens, Lieve; Keough, Dianne T.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:247036 |
3 |
Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases |
Klejch, Tomáš; Pohl, Radek; Janeba, Zlatko; Sun, Minghan; Keough, Dianne T.; Guddat, Luke W.; Hocková, Dana |
Article |
University of Queensland [UQ eSpace] |
|
97 |
Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases |
Hockova, Dana; Janeba, Zlatko; Naesens, Lieve; Edstein, Michael D.; Chavchich, Marina; Keough, Dianne T.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:367518 |
82 |
Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections |
Garcia, Mario D.; Chua, Sheena M. H.; Low, Yu-Shang; Lee, Yu-Ting; Agnew-Francis, Kylie; Wang, Jian-Guo; Nouwens, Amanda; Lonhienne, Thierry; Williams, Craig M.; Fraser, James A.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
|
26 |
Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides |
Garcia, Mario Daniel; Wang, Jian-Guo; Lonhienne, Thierry; Guddat, Luke William |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:591835 |
66 |
Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity |
Patel, Khushboo; Teran, David; Zheng, Shan; Kandale, Ajit; Garcia, Mario; Lv, You; Schembri, Mark A; McGeary, Ross P; Schenk, Gerhard; Guddat, Luke William |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:696927 |
6 |
Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP , GMP and XMP |
Terán, David; Doleželová, Eva; Keough, Dianne T.; Hocková, Dana; Zíková, Alena; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
|
2 |
Crystallization and preliminary diffraction studies of native and selenomethionine CcmG (CycY, DsbE) |
Edeling, M. A.; Guddat, L. W.; Fabianek, R. A.; Halliday, J. A.; Jones, A.; Thony-Meyer, L.; Martin, J. L. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:59328 |
43 |
Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis |
Millers, E. K. I.; Masci, P. P.; Lavin, M. F.; de Jersey, J.; Guddat, L. W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:79800 |
29 |
Crystallization and preliminary X-ray diffraction data for a purple acid phosphastase from sweet potato |
Schenk, G.; Carrington, L.; Hamilton, S. E.; De Jersey, J.; Guddat, L. W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:143226 |
54 |
Crystallization and preliminary X-ray diffraction studies of mammalian purple acid phosphatase |
Guddat, L. W.; McAlpine, A. S.; Hume, D. A.; De Jersey, J.; Hamilton, S. E.; Martin, J. L. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:35798 |
32 |
Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl |
Pang, S. S.; Guddat, L. W.; Duggleby, R. G. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:70933 |
91 |
Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroyacid synthase |
Pang, S. S.; Guddat, L. W.; Duggleby, R.G. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:58675 |
75 |
Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae |
Pang, S. S.; Guddat, L. W.; Duggleby, R.G. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:61999 |
55 |
Deacidification of grass silage press juice by continuous production of acetoin from its lactate via an immobilized enzymatic reaction cascade |
Hohagen, Hendrik; Schwarz, Dominik; Schenk, Gerhard; Guddat, Luke W.; Schieder, Doris; Carsten, Jörg; Sieber, Volker |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:688229 |
55 |
Discovery of a pyrimidine-dione derivative with potent inhibitory activity against Mycobacterium tuberculosis ketol-acid reductoisomerase |
Lin, Xin; Kurz, Julia; Patel, Khushboo; Wun, Shun Jie; Hussein, Waleed; Lonhienne, Thierry; West, Nicholas P.; McGeary, Ross P.; Schenk, Gerhard; Guddat, Luke William |
Article |
University of Queensland [UQ eSpace] |
|
6 |
Discovery, synthesis and evaluation of a novel ketol-acid reductoisomerase inhibitor |
Bayaraa, Tenuun; Kurz, Julia L.; Patel, Khushboo M.; Hussein, Waleed M.; Bilyj, Jessica K.; West, Nicholas P.; Schenk, Gerhard; McGeary, Ross P.; Guddat, Luke William |
Article |
University of Queensland [UQ eSpace] |
|
41 |
Engineering highly functional thermostable proteins using ancestral sequence reconstruction |
Gumulya, Yosephin; Baek, Jong-Min; Wun, Shun-Jie; Thomson, Raine E. S.; Harris, Kurt L.; Hunter, Dominic J. B.; Behrendorff, James B. Y. H.; Kulig, Justyna; Zheng, Shan; Wu, Xueming; Wu, Bin; Stok, Jeanette E.; De Voss, James J.; Schenk, Gerhard; Jurva, U |
Article |
University of Queensland [UQ eSpace] |
|
182 |
Facile crystallization of Escherichia coli ketol-acid reductoisomerase |
McCourt, J. A.; Tyagi, R.; Guddat, L. W.; Biou, V.; Duggleby, R. G. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:70934 |
197 |
High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism |
Lonhienne, Thierry; Garcia, Mario D.; Noble, Chris; Harmer, Jeffrey; Fraser, James A.; Williams, Craig M.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:717647 |
4 |
Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomerase |
Tadrowski, Sonya; Pedroso, Marcelo M.; Sieber, Volker; Larrabee, James A.; Guddat, Luke W.; Schenk, Gerhard |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:386392 |
16 |
Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase |
Pang, S. S.; Guddat, L. W.; Duggleby, R. G. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:65269 |
42 |
Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases |
Lukáč, Miloš; Hocková, Dana; Keough, Dianne T.; Guddat, Luke W.; Janeba, Zlatko |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:418014 |
74 |
Oligomeric state of hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis |
Eng, Wai Soon; Keough, Dianne T.; Hockova, Dana; Winzor, Donald J.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:423055 |
96 |
Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics |
Hussein, Waleed M.; Feder, Daniel; Schenk, Gerhard; Guddat, Luke W.; McGeary, Ross P. |
Article |
University of Queensland [UQ eSpace] |
|
41 |
Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase |
Eng, Wai Soon; Rejman, Dominik; Pohl, Radek; West, Nicholas P.; Woods, Kyra; Naesens, Lieve M.J.; Keough, Dianne T.; Guddat, Luke W. |
Article |
University of Queensland [UQ eSpace] |
|
93 |
Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs |
Spacek, Petr; Keough, Dianne T.; Chavchich, Marina; Dracinsky, Martin; Janeba, Zlatko; Naesens, Lieve; Edstein, Michael D.; Guddat, Luke W.; Hockova, Dana |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:649234 |
80 |
Synthesis of the seco-limonoid BCD ring system identifies a Hsp90 chaperon machinery (p23) inhibitor |
Pinkerton, David M.; Chow, Sharon; Eisa, Nada H.; Kainth, Kashish; Vanden Berg, Timothy J.; Burns, Jed M.; Guddat, Luke W.; Savage, G. Paul; Chadli, Ahmed; Williams, Craig M. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:4747986 |
23 |
The binding mode of an ADP analogue to a metallohydrolase mimics the likely transition state |
Feder, Daniel; Gahan, Lawrence R.; McGeary, Ross P.; Guddat, Luke W.; Schenk, Gerhard |
Article |
University of Queensland [UQ eSpace] |
|
6 |
The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate |
Pang, S. S.; Duggleby, R. G.; Schowen, R. L.; Guddat, L. W. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:70930 |
15 |
The structure-activity relationship in herbicidal monosubstituted sulfonylureas |
Li, Zheng-Ming; Ma, Yi; Guddat, Luke; Cheng, Pei-Quan; Wang, Jian-Guo; Pangi, Siew S.; Dong, Yu-Hui; Lai, Cheng-Ming; Wang, Ling-Xiu; Jia, Guo-Feng; Li, Yong-Hong; Wang, Su-Hua; Liu, Jie; Zhao, Wei-Guang; Wang, Bao Lei |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:269443 |
1 |
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties |
Bourne, P. C.; Ramsland, P. A.; Shan, L.; Fan, Z. C.; DeWitt, C. R.; Shultz, B. B.; Terzyan, S. S.; Moomaw, C. R.; Slaughter, C. A.; Guddat, L. W.; Edmundson, A. B. |
Article |
University of Queensland [UQ eSpace] |
https://espace.library.uq.edu.au/view/UQ:109964 |
80 |