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Author statistics

Author Identifier Number of Items Total Downloads
Guddat, L https://orcid.org/0000-0002-8204-8408 32 1713

Items

Title Author(s) IrusType Repository Item URL Total Downloads
6-Oxopurine phosphoribosyltransferase: A target for the development of antimalarial drugs de Jersey, John; Holý, Antonín; Hocková, Dana; Naesens, Lieve; Keough, Dianne T.; Guddat, Luke W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:247036 3
Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases Klejch, Tomáš; Pohl, Radek; Janeba, Zlatko; Sun, Minghan; Keough, Dianne T.; Guddat, Luke W.; Hocková, Dana Article University of Queensland [UQ eSpace] 97
Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases Hockova, Dana; Janeba, Zlatko; Naesens, Lieve; Edstein, Michael D.; Chavchich, Marina; Keough, Dianne T.; Guddat, Luke W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:367518 82
Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections Garcia, Mario D.; Chua, Sheena M. H.; Low, Yu-Shang; Lee, Yu-Ting; Agnew-Francis, Kylie; Wang, Jian-Guo; Nouwens, Amanda; Lonhienne, Thierry; Williams, Craig M.; Fraser, James A.; Guddat, Luke W. Article University of Queensland [UQ eSpace] 26
Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides Garcia, Mario Daniel; Wang, Jian-Guo; Lonhienne, Thierry; Guddat, Luke William Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:591835 66
Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity Patel, Khushboo; Teran, David; Zheng, Shan; Kandale, Ajit; Garcia, Mario; Lv, You; Schembri, Mark A; McGeary, Ross P; Schenk, Gerhard; Guddat, Luke William Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:696927 6
Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP , GMP and XMP Terán, David; Doleželová, Eva; Keough, Dianne T.; Hocková, Dana; Zíková, Alena; Guddat, Luke W. Article University of Queensland [UQ eSpace] 2
Crystallization and preliminary diffraction studies of native and selenomethionine CcmG (CycY, DsbE) Edeling, M. A.; Guddat, L. W.; Fabianek, R. A.; Halliday, J. A.; Jones, A.; Thony-Meyer, L.; Martin, J. L. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:59328 43
Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis Millers, E. K. I.; Masci, P. P.; Lavin, M. F.; de Jersey, J.; Guddat, L. W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:79800 29
Crystallization and preliminary X-ray diffraction data for a purple acid phosphastase from sweet potato Schenk, G.; Carrington, L.; Hamilton, S. E.; De Jersey, J.; Guddat, L. W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:143226 54
Crystallization and preliminary X-ray diffraction studies of mammalian purple acid phosphatase Guddat, L. W.; McAlpine, A. S.; Hume, D. A.; De Jersey, J.; Hamilton, S. E.; Martin, J. L. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:35798 32
Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl Pang, S. S.; Guddat, L. W.; Duggleby, R. G. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:70933 91
Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroyacid synthase Pang, S. S.; Guddat, L. W.; Duggleby, R.G. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:58675 75
Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae Pang, S. S.; Guddat, L. W.; Duggleby, R.G. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:61999 55
Deacidification of grass silage press juice by continuous production of acetoin from its lactate via an immobilized enzymatic reaction cascade Hohagen, Hendrik; Schwarz, Dominik; Schenk, Gerhard; Guddat, Luke W.; Schieder, Doris; Carsten, Jörg; Sieber, Volker Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:688229 55
Discovery of a pyrimidine-dione derivative with potent inhibitory activity against Mycobacterium tuberculosis ketol-acid reductoisomerase Lin, Xin; Kurz, Julia; Patel, Khushboo; Wun, Shun Jie; Hussein, Waleed; Lonhienne, Thierry; West, Nicholas P.; McGeary, Ross P.; Schenk, Gerhard; Guddat, Luke William Article University of Queensland [UQ eSpace] 6
Discovery, synthesis and evaluation of a novel ketol-acid reductoisomerase inhibitor Bayaraa, Tenuun; Kurz, Julia L.; Patel, Khushboo M.; Hussein, Waleed M.; Bilyj, Jessica K.; West, Nicholas P.; Schenk, Gerhard; McGeary, Ross P.; Guddat, Luke William Article University of Queensland [UQ eSpace] 41
Engineering highly functional thermostable proteins using ancestral sequence reconstruction Gumulya, Yosephin; Baek, Jong-Min; Wun, Shun-Jie; Thomson, Raine E. S.; Harris, Kurt L.; Hunter, Dominic J. B.; Behrendorff, James B. Y. H.; Kulig, Justyna; Zheng, Shan; Wu, Xueming; Wu, Bin; Stok, Jeanette E.; De Voss, James J.; Schenk, Gerhard; Jurva, U Article University of Queensland [UQ eSpace] 182
Facile crystallization of Escherichia coli ketol-acid reductoisomerase McCourt, J. A.; Tyagi, R.; Guddat, L. W.; Biou, V.; Duggleby, R. G. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:70934 197
High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism Lonhienne, Thierry; Garcia, Mario D.; Noble, Chris; Harmer, Jeffrey; Fraser, James A.; Williams, Craig M.; Guddat, Luke W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:717647 4
Metal ions play an essential catalytic role in the mechanism of ketol-acid reductoisomerase Tadrowski, Sonya; Pedroso, Marcelo M.; Sieber, Volker; Larrabee, James A.; Guddat, Luke W.; Schenk, Gerhard Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:386392 16
Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase Pang, S. S.; Guddat, L. W.; Duggleby, R. G. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:65269 42
Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases Lukáč, Miloš; Hocková, Dana; Keough, Dianne T.; Guddat, Luke W.; Janeba, Zlatko Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:418014 74
Oligomeric state of hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis Eng, Wai Soon; Keough, Dianne T.; Hockova, Dana; Winzor, Donald J.; Guddat, Luke W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:423055 96
Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics Hussein, Waleed M.; Feder, Daniel; Schenk, Gerhard; Guddat, Luke W.; McGeary, Ross P. Article University of Queensland [UQ eSpace] 41
Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase Eng, Wai Soon; Rejman, Dominik; Pohl, Radek; West, Nicholas P.; Woods, Kyra; Naesens, Lieve M.J.; Keough, Dianne T.; Guddat, Luke W. Article University of Queensland [UQ eSpace] 93
Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs Spacek, Petr; Keough, Dianne T.; Chavchich, Marina; Dracinsky, Martin; Janeba, Zlatko; Naesens, Lieve; Edstein, Michael D.; Guddat, Luke W.; Hockova, Dana Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:649234 80
Synthesis of the seco-limonoid BCD ring system identifies a Hsp90 chaperon machinery (p23) inhibitor Pinkerton, David M.; Chow, Sharon; Eisa, Nada H.; Kainth, Kashish; Vanden Berg, Timothy J.; Burns, Jed M.; Guddat, Luke W.; Savage, G. Paul; Chadli, Ahmed; Williams, Craig M. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:4747986 23
The binding mode of an ADP analogue to a metallohydrolase mimics the likely transition state Feder, Daniel; Gahan, Lawrence R.; McGeary, Ross P.; Guddat, Luke W.; Schenk, Gerhard Article University of Queensland [UQ eSpace] 6
The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate Pang, S. S.; Duggleby, R. G.; Schowen, R. L.; Guddat, L. W. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:70930 15
The structure-activity relationship in herbicidal monosubstituted sulfonylureas Li, Zheng-Ming; Ma, Yi; Guddat, Luke; Cheng, Pei-Quan; Wang, Jian-Guo; Pangi, Siew S.; Dong, Yu-Hui; Lai, Cheng-Ming; Wang, Ling-Xiu; Jia, Guo-Feng; Li, Yong-Hong; Wang, Su-Hua; Liu, Jie; Zhao, Wei-Guang; Wang, Bao Lei Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:269443 1
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties Bourne, P. C.; Ramsland, P. A.; Shan, L.; Fan, Z. C.; DeWitt, C. R.; Shultz, B. B.; Terzyan, S. S.; Moomaw, C. R.; Slaughter, C. A.; Guddat, L. W.; Edmundson, A. B. Article University of Queensland [UQ eSpace] https://espace.library.uq.edu.au/view/UQ:109964 80
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