Title |
Author(s) |
IrusType |
Repository |
Item URL |
Total Downloads |
Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors |
orcid:0000-0002-4073-0505; orcid:0000-0003-2948-2413; Blaszczyk, M; Harmer, NJ; Chirgadze, DY; Ascher, DB; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216421 |
27 |
Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase |
orcid:0000-0002-3963-4540; orcid:0000-0002-3101-1138; orcid:0000-0003-2948-2413; orcid:0000-0002-5910-7625; Chai, SY; Yeatman, HR; Parker, MW; Ascher, DB; Thompson, PE; Mulvey, HT; Albiston, AL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216428 |
26 |
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Ascher, DB; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216424 |
21 |
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability |
orcid:0000-0003-2948-2413; Rodrigues, CHM; Pires, DE; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216409 |
28 |
Evolution of carbapenem resistance in Acinetobacter baumannii during a prolonged infection |
orcid:0000-0001-9661-5293; orcid:0000-0003-2948-2413; orcid:0000-0003-3613-4839; orcid:0000-0001-8349-0778; Hawkey, J; Ascher, DB; Judd, LM; Wick, RR; Kostoulias, X; Cleland, H; Spelman, DW; Padiglione, A; Peleg, AY; Holt, KE |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/212108 |
33 |
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding |
orcid:0000-0002-5225-397X; orcid:0000-0002-8602-8009; orcid:0000-0002-8440-1690; orcid:0000-0003-2948-2413; orcid:0000-0002-2708-8992; Sigurdardottir, AG; Winter, A; Sobkowicz, A; Fragai, M; Chirgadze, D; Ascher, DB; Blundell, TL; Gherardi, E |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216425 |
19 |
Familial STAG2 germline mutation defines a new human cohesinopathy |
orcid:0000-0001-7879-0450; orcid:0000-0001-8770-8009; orcid:0000-0003-2948-2413; Soardi, FC; Machado-Silva, A; Linhares, ND; Zheng, G; Qu, Q; Pena, HB; Martins, TMM; Vieira, HGS; Pereira, NB; Melo-Minardi, RC; Gomes, CC; Gomez, RS; Gomes, DA; Pires, DEV; |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216412 |
41 |
Flexibility and small pockets at protein-protein interfaces: New insights into druggability |
orcid:0000-0001-6094-0975; orcid:0000-0003-2948-2413; Jubb, H; Blundell, TL; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216420 |
23 |
Fragment-Based Approach to Targeting Inosine-5 '-monophosphate Dehydrogenase (IMPDH) from &ITMycobacterium tuberculosis&IT |
orcid:0000-0003-4526-7895; orcid:0000-0001-9002-2489; orcid:0000-0003-0205-5630; orcid:0000-0003-4824-9115; orcid:0000-0003-2948-2413; Trapero, A; Pacitto, A; Singh, V; Sabbah, M; Coyne, AG; Mizrahi, V; Blundell, TL; Ascher, DB; Abell, C |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216410 |
44 |
Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance |
orcid:0000-0003-2948-2413; orcid:0000-0003-1152-4312; Pandurangan, AP; Ascher, DB; Thomas, SE; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216413 |
27 |
Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma |
orcid:0000-0003-2948-2413; orcid:0000-0002-3004-2119; orcid:0000-0002-8539-8753; orcid:0000-0003-0550-3400; orcid:0000-0002-6226-6918; Jafri, M; Wake, NC; Ascher, DB; Pires, DEV; Gentle, D; Morris, MR; Rattenberry, E; Simpson, MA; Trembath, RC; Weber, A; |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/168257 |
2 |
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis |
orcid:0000-0003-2049-870X; orcid:0000-0001-6132-6168; orcid:0000-0002-4660-1245; orcid:0000-0003-4251-8898; orcid:0000-0002-2784-9560; orcid:0000-0003-3037-2836; orcid:0000-0001-8212-9884; orcid:0000-0003-0532-8331; orcid:0000-0002-8344-2626; orcid:0000-0 |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/173323 |
2 |
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Chen, J; Blundell, TL; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216419 |
24 |
Kinact: a computational approach for predicting activating missense mutations in protein kinases |
orcid:0000-0003-2948-2413; Rodrigues, CHM; Ascher, DB; Pires, DE |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216408 |
22 |
mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signatures |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/145348 |
5 |
mCSM-NA: predicting the effects of mutations on protein-nucleic acids interactions |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216414 |
27 |
mCSM: predicting the effects of mutations in proteins using graph-based signatures |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Ascher, DB; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216427 |
69 |
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance |
orcid:0000-0001-8323-7019; orcid:0000-0003-2948-2413; orcid:0000-0002-3004-2119; orcid:0000-0002-3828-5473; orcid:0000-0001-8587-1849; orcid:0000-0002-1755-2819; Phelan, J; Coll, F; McNerney, R; Ascher, DB; Pires, DEV; Furnham, N; Coeck, N; Hill-Cawthorne |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/145349 |
3 |
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures |
orcid:0000-0002-3004-2119; orcid:0000-0002-2708-8992; orcid:0000-0003-2948-2413; Pires, DEV; Blundell, TL; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216422 |
57 |
Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes |
orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Pires, DEV; Blundell, TL; Ascher, DB |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216423 |
24 |
SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity |
orcid:0000-0003-2948-2413; orcid:0000-0002-3004-2119; orcid:0000-0002-9306-1747; orcid:0000-0002-6226-6918; Casey, RT; Ascher, DB; Rattenberry, E; Izatt, L; Andrews, KA; Simpson, HL; Challis, B; Park, S-M; Bulusu, VR; Lalloo, F; Pires, DEV; West, H; Clark |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216415 |
37 |
SDM: a server for predicting effects of mutations on protein stability |
orcid:0000-0001-7168-7143; orcid:0000-0003-2948-2413; Pandurangan, AP; Ochoa-Montano, B; Ascher, DB; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216429 |
38 |
Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae |
orcid:0000-0003-2948-2413; Vedithi, SC; Malhotra, S; Das, M; Daniel, S; Kishore, N; George, A; Arumugam, S; Rajan, L; Ebenezer, M; Ascher, DB; Arnold, E; Blundell, TL |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/212109 |
33 |
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis |
orcid:0000-0001-9002-2489; orcid:0000-0003-4031-4648; orcid:0000-0001-7315-1553; orcid:0000-0002-5887-8137; orcid:0000-0003-2948-2413; Singh, V; Donini, S; Pacitto, A; Sala, C; Hartkoorn, RC; Dhar, N; Keri, G; Ascher, DB; Mondesert, G; Vocat, A; Lupien, A |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216416 |
61 |
The Presence, Persistence and Functional Properties of Plasmodium vivax Duffy Binding Protein II Antibodies Are Influenced by HLA Class II Allelic Variants |
orcid:0000-0002-2364-9772; orcid:0000-0002-3004-2119; orcid:0000-0003-2948-2413; Kano, FS; Souza-Silva, FA; Torres, LM; Lima, BAS; Sousa, TN; Alves, JRS; Rocha, RS; Fontes, CJF; Sanchez, BAM; Adams, JH; Brito, CFA; Pires, DEV; Ascher, DB; Sell, AM; Carval |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216417 |
24 |
Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD |
orcid:0000-0003-2948-2413; Andrews, KA; Ascher, DB; Pires, DEV; Barnes, DR; Vialard, L; Casey, RT; Bradshaw, N; Adlard, J; Aylwin, S; Brennan, P; Brewer, C; Cole, T; Cook, JA; Davidson, R; Donaldson, A; Fryer, A; Greenhalgh, L; Hodgson, SV; Irving, R; Lal |
Article |
University of Melbourne [Minerva Access] |
http://hdl.handle.net/11343/216411 |
38 |